Methyl 3-chloro-3-oxopropanoate

Names

[ Name ]:
Methyl 3-chloro-3-oxopropanoate

[Synonym ]:
Propanoic acid, 3-chloro-3-oxo-, methyl ester
Methyl (Chloroformyl)acetate
methyl chlorocarbonyl acetate
3-methoxy-3-oxopropanoyl chloride
METHYL CHLOROFORMYLACETATE
methyl-3-chlorooxopropionate
METHYL 3-CHLORO-3-OXOPROPIONATE
Methyl Malonyl Chloride
methyl 2-chloroformylacetate
(Chloroformyl)acetic Acid Methyl Ester
Methyl Malonyl chloride 25GR
MFCD00013657
methoxycarbonylacetyl chloride
EINECS 253-540-6
Methyl 3-chloro-3-oxopropanoate
Mehtyl Malonyl Chloride
3-Chloro-3-oxopropionic Acid Methyl Ester

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
167.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₅ClO₃

[ Molecular Weight ]:
136.534

[ Flash Point ]:
80.0±0.0 °C

[ Exact Mass ]:
135.992722

[ PSA ]:
43.37000

[ LogP ]:
0.56

[ Vapour Pressure ]:
1.7±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.425

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Synthesis and mesomorphic properties of calamitic malonates and cyanoacetates tethered to 4-cyanobiphenyls.

Beilstein J. Org. Chem. 8 , 371-8, (2012)

4-Cyano-1,1'-biphenyl derivatives bearing ω-hydroxyalkyl substituents were reacted with methyl 3-chloro-3-oxopropionate or cyanoacetic acid, giving liquid-crystalline linear malonates and cyanoacetate...

A general solid phase synthesis of 4-substituted quinolinones via Pd-catalyzed cross coupling. Xu C, et al.

Tetrahedron Lett. 47(28) , 4885-88, (3006)

Solvent-free microwave-assisted Bingel reaction in carbon nanohorns. Economopoulos SP, et al.

J. Mater. Chem. 19(39) , 7326-31, (2009)