alpha-1,3-Galactosyltransferase(GTB)

Names

[ CAS No. ]:
37257-33-3

[ Name ]:
alpha-1,3-Galactosyltransferase(GTB)

Biological Activity

[Description]:

alpha-1,3-Galactosyltransferase(GTB) (alpha3GT) catalyzes the synthesis of the xenoantigen or α-galactose (α-Gal) epitope. alpha-1,3-Galactosyltransferase(GTB) transfers galactose from UDP-Gal to type 1 or type 2, αFuc1→2βGal-R (H)-terminating acceptors[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite


[References]

[1]. Sandra L Marcus, et al. A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase. J Biol Chem. 2003 Apr 4;278(14):12403-5.  

[2]. Nethaji Thiyagarajan, et al. Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Sci Rep. 2012;2:940.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds