AMB639752

Names

[ Name ]:
AMB639752

Biological Activity

[Description]:

AMB639752 is a potent DGKα inhibitor. AMB639752 restores restimulation induced cell death (RICD) in SAP deficient lymphocytes by inhibiting DGKα in intact cells. AMB639752 can be used for X-linked lymphoproliferative disease 1(XLP-1) research[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Velnati S, et.al. Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening. Eur J Med Chem. 2019 Feb 15;164:378-390.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₃N₃O₃

[ Molecular Weight ]:
365.43

Related Compounds

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