Disodium 6-O-phosphonato-D-glucose

Names

[ Name ]:
Disodium 6-O-phosphonato-D-glucose

[Synonym ]:
D-glucose 6-phosphate disodium salt
glucose 6-(disodium phosphate)
G-6-P-NA2
D-Glucose 6-(disodium phosphate)
ROBINSON ESTER
ROBINSON ESTER DISODIUM SALT
D-Glucose, 6-(dihydrogen phosphate), sodium salt (1:2)
Glucose-6-phosphoric acid Na2
Glucose-6-phosphat Dinatriumsalz
sodium glucose-6-phosphate
Disodium 6-O-phosphonato-D-glucose
D-Glucose 6-phosphate disodium salt hydrate,G-6-P-Na2,Robison ester
ROBISON ESTER DISODIUM SALT
sodium salt of glucose-6-phosphate
G-6-P-Na2 Robison ester
Glucose-6-phosphate,Disodium Salt
Glucose-6-phosphate-Na2-salt
GLUCOSE-6-PHOSPHATE,DISODIUM
EINECS 222-938-1
MFCD00136037

Biological Activity

[Description]:

D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

This dianion is very common in cells as the majority of glucose entering a cell will become phosphorylated in this way[1].

[References]

[1]. Olsen BB, et al. Linked Hexokinase and Glucose-6-Phosphatase Activities Reflect Grade of Ovarian Malignancy. Mol Imaging Biol. 2018 Jul 9.

Chemical & Physical Properties

[ Boiling Point ]:
667.8ºC

[ Molecular Formula ]:
C₆H₁₁Na₂O₉P

[ Molecular Weight ]:
304.099

[ Flash Point ]:
357.7ºC

[ Exact Mass ]:
303.993622

[ PSA ]:
180.22000

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 0.1 g/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-27-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2919900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2919900090

[ Summary ]:
2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles

Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

PLoS ONE 10(1) , e0117842, (2015)

Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and n...

A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells.

J. Biol. Chem. 284 , 30766-30774, (2009)

Ether-type inositol phospholipids are ubiquitously distributed in Archaea membranes. The present paper describes a novel biosynthetic pathway of the archaeal inositol phospholipid. To study the biosyn...

The role of glucose 6-phosphate in the control of glycogen synthase.

FASEB J. 11(7) , 544-58, (1997)

Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main...