2,5-Difluoronitrobenzene
Names
[ CAS No. ]:
364-74-9
[ Name ]:
2,5-Difluoronitrobenzene
[Synonym ]:
2,5-Difluoro-1-nitrobenzene
1,4-Difluoro-2-nitrobenzene
2,5-Difluoronitroben
Benzene, 1,4-difluoro-2-nitro-
3,5-diflurobenzalcohol
EINECS 206-663-4
2,5-difluoronitro-benzene
1,4-difluoro-2-nitro-benzen
1-Nitro-2,5-difluorobenzene
2,5-Difluoronitrobenzene
2,4-DIFLUOROCINNAMIC ACD
MFCD00007054
1-fluoro-2-nitro-4-fluorobenzene
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
206.5±0.0 °C at 760 mmHg
[ Melting Point ]:
−11.7 °C(lit.)
[ Molecular Formula ]:
C6H3F2NO2
[ Molecular Weight ]:
159.090
[ Flash Point ]:
90.0±0.0 °C
[ Exact Mass ]:
159.013184
[ PSA ]:
45.82000
[ LogP ]:
1.71
[ Vapour Pressure ]:
0.3±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.510
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ5715000
- CHEMICAL NAME :
- Benzene, 1,4-difluoro-2-nitro-
- CAS REGISTRY NUMBER :
- 364-74-9
- BEILSTEIN REFERENCE NO. :
- 2210200
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H3-F2-N-O2
- MOLECULAR WEIGHT :
- 159.10
- WISWESSER LINE NOTATION :
- WNR BF EF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 160 nL/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,217,1983
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
2810
[ WGK Germany ]:
3
[ RTECS ]:
CZ5715000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2904909090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2904909090
[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
J. Phys. Chem. B 114(40) , 12914-25, (2010)
This work reports the experimental and computational thermochemical study performed on three difluorinated nitrobenzene isomers: 2,4-difluoronitrobenzene (2,4-DFNB), 2,5-difluoronitrobenzene (2,5-DFNB...
Different metabolic pathways of 2,5-difluoronitrobenzene and 2,5-difluoroaminobenzene compared to molecular orbital substrate characteristics.Chem. Biol. Interact. 94(1) , 49-72, (1995)
The in vivo metabolite patterns of 2,5-difluoroaminobenzene and of its nitrobenzene analogue, 2,5-difluoronitrobenzene, were determined using 19F NMR analysis of urine samples. Results obtained demons...
In vitro metabolism of 5-fluoro-2-glutathionyl-nitrobenzene by kidney proximal tubular cells studied by 19F-NMR.Chem. Biol. Interact. 98(2) , 97-112, (1995)
Proximal tubular biotransformation of the glutathionyl (GSH) conjugate derived from 2,5-difluoronitrobenzene (5-fluoro-2-glutathionyl-nitrobenzene) was studied by means of 19F-NMR. This method allows ...