RBC10

Names

[ Name ]:
RBC10

[Synonym ]:
11-(2-Chlorophenyl)-10-pentanoyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
1H-Dibenzo[b,e][1,4]diazepin-1-one, 11-(2-chlorophenyl)-2,3,4,5,10,11-hexahydro-10-(1-oxopentyl)-

Biological Activity

[Description]:

RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[References]

[1]. Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014;515(7527):443-447.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
616.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₅ClN₂O₂

[ Molecular Weight ]:
408.92

[ Flash Point ]:
326.5±31.5 °C

[ Exact Mass ]:
408.160461

[ LogP ]:
5.00

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.637

Related Compounds

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