D-Mannoheptulose

Names

[ Name ]:
D-Mannoheptulose

[Synonym ]:
(3S,4S,5R,6R)-1,3,4,5,6,7-Hexahydroxy-2-heptanone
D-manno-2-Heptulose
D-MANNOHEPTULOSE
(3S,4S,5R,6R)-1,3,4,5,6,7-Hexahydroxyheptan-2-one
D-manno-Heptulose
D-manno-Heptulose (8CI)
D-manno-Hept-2-ulose
D-manno-Ketoheptose
Mannoheptulose

Biological Activity

[Description]:

D-Mannoheptulose is a major non-structural carbohydrate in avocado. D-mannoheptulose is a specific inhibitor of D-glucose phosphorylation. D-Mannoheptulose can block insulin release and utilization of carbohydrate in rat[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. D-mannoheptulose and perseitol in ‘Hass’ avocado: Metabolism in seed and mesocarp tissue. South African Journal of Botany. 2012 Mar; 79:159-165.

[2]. Courtois P, et al. D-mannoheptulose phosphorylation by hexokinase isoenzymes. Int J Mol Med. 2001 Apr;7(4):359-63.

[3]. Frenkel G, et al. Metabolic effects of insulin blockade by D-mannoheptulose in the sand rat (Psammomys obesus) and the rat. Gen Comp Endocrinol. 1972 Oct;19(2):341-4.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
628.0±55.0 °C at 760 mmHg

[ Melting Point ]:
151-152ºC

[ Molecular Formula ]:
C₇H₁₄O₇

[ Molecular Weight ]:
210.182

[ Flash Point ]:
347.6±28.0 °C

[ Exact Mass ]:
210.073959

[ PSA ]:
130.61000

[ LogP ]:
-2.47

[ Vapour Pressure ]:
0.0±4.2 mmHg at 25°C

[ Index of Refraction ]:
1.597

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2914400090

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Related Compounds

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