3-Keto petromyzonol

Names

[ Name ]:
3-Keto petromyzonol

[Synonym ]:
(5α,7α,9ξ,12α,20R)-7,12,24-Trihydroxycholan-3-one
7ALPHA,12ALPHA,24-TRIHYDROXY-5ALPHA-CHOLANE-3-ONE
Cholan-3-one, 7,12,24-trihydroxy-, (5α,7α,9ξ,12α,20R)-
3-ketopetromyzonol

Biological Activity

[Description]:

3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Others >> Others

[References]

[1]. Yu-Wen Chung-Davidson, et al. Pheromonal Bile Acid 3-ketopetromyzonol Sulfate Primes the Neuroendocrine System in Sea Lamprey. BMC Neurosci. 2013 Jan 20;14:11.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
543.7±50.0 °C at 760 mmHg

[ Melting Point ]:
195ºC

[ Molecular Formula ]:
C₂₄H₄₀O₄

[ Molecular Weight ]:
392.572

[ Flash Point ]:
296.7±26.6 °C

[ Exact Mass ]:
392.292664

[ PSA ]:
77.76000

[ LogP ]:
2.30

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.545

Related Compounds

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