1-Methyl-3-phenoxybenzene

Names

[ Name ]:
1-Methyl-3-phenoxybenzene

[Synonym ]:
Phenyl m-tolyl ether
EINECS 222-716-4
3-Methyldiphenyl Ether
1-Methyl-3-phenoxybenzene
3-Phenoxytoluene
3-methyl diphenyl ether
Benzene, 1-methyl-3-phenoxy-
m-Methylphenyl phenyl ether
BENZENE,1-METHYL-3-PHENOXY
3-Methylphenyl phenyl ether
meta-phenoxy-toluene
m-Phenoxytoluene
Ether,phenyl m-tolyl
m-Tolyl Phenyl Ether
MFCD00008531

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
269.1±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₂O

[ Molecular Weight ]:
184.234

[ Flash Point ]:
110.8±14.4 °C

[ Exact Mass ]:
184.088821

[ PSA ]:
9.23000

[ LogP ]:
4.67

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.566

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA6142000

CHEMICAL NAME :: Benzene, 1-methyl-3-phenoxy-

CAS REGISTRY NUMBER :: 3586-14-9

BEILSTEIN REFERENCE NO. :: 2045714

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C13-H12-O

MOLECULAR WEIGHT :: 184.25

WISWESSER LINE NOTATION :: 1R COR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2509 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 50 ug/plate

REFERENCE :: CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 21,240,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3741 No. of Facilities: 36 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 145 (estimated) No. of Female Employees: 73 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DA6142000

[ HS Code ]:
2909309090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Metabolism of 3-methyldiphenyl ether by Sphingomonas sp. SS31.

FEMS Microbiol. Lett. 75(2-3) , 253-8, (1992)

The bacterium Sphingomonas sp. SS31, which was obtained from the diphenyl ether-degrading strain Sphingomonas sp. SS3 by an adaptation process, utilized 3-methyldiphenyl ether for growth in addition t...

First steps towards a Zn/Co(III)sep-driven P450 BM3 reactor.

Appl. Microbiol. Biotechnol. 91(4) , 989-99, (2011)

Cytochrome P450s are synthetically attractive hydroxylation catalysts. For cell-free applications, a constant supply of NAD(P)H can be very costly. Mediators such as Zn/Co(III)sep can be an alternativ...