L-Glutamic acid,N-[4-[[2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethyl]amino]benzoyl]- (9CI)
Names
[ CAS No. ]:
3566-25-4
[ Name ]:
L-Glutamic acid,N-[4-[[2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethyl]amino]benzoyl]- (9CI)
[Synonym ]:
N-{4-[2-(2-amino-4-oxo-3,4-dihydro-pteridin-6-yl)-ethylamino]-benzoyl}-glutamic acid
2-Glutamic acid,N-(4-(2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethylamino)benzoyl)-(9ci)
L-Glutamic acid,N-(4-((2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethyl)amino)benzoyl)-(9ci)
Glutamic acid,N-(p-((2-(2-amino-4-hydroxy-6-pteridinyl)ethyl)amino)benzoyl)
N-<4-(<2-(2-Amino-4-hydroxy-6-pteridinyl)-aethyl>-amino)-benzoyl-L-glutaminsaeure
N-[p-[[2-(2-Amino-4-hydroxy-6-pteridinyl)ethyl]amino]benzoyl]-L-glutamic acid
Homofolsaeure
Homofolate
Chemical & Physical Properties
[ Density]:
1.64g/cm3
[ Molecular Formula ]:
C20H21N7O6
[ Molecular Weight ]:
455.42400
[ Exact Mass ]:
455.15500
[ PSA ]:
213.28000
[ LogP ]:
1.04280
[ Index of Refraction ]:
1.744
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA0601000
- CHEMICAL NAME :
- Glutamic acid, N-(p-((2-(2-amino-4-hydroxy-6-pteridinyl)ethyl)amino) benzoyl)-
- CAS REGISTRY NUMBER :
- 3566-25-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H21-N7-O6
- MOLECULAR WEIGHT :
- 455.48
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EQ H2MR DVMYVQ2VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12800 ug/kg
- SEX/DURATION :
- female 8-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - live birth index (measured after birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 14,1541,1974