Benzo[b]thiophene-2-carboxaldehyde

Names

[ Name ]:
Benzo[b]thiophene-2-carboxaldehyde

[Synonym ]:
Thianaphthene-2-carboxaldehyde
1-Benzothiophene-2-carbaldehyde
benzothiophene-2-carboxaldehyde
2-Formylbenzo[b]thiophene
MFCD01075041
Benzo[b]-2-thiophenecarboxaldehyde
2-benzothiophenecarboxaldehyde
Benzo[b]thiophene-2-carboxaldehyde

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
303.2±15.0 °C at 760 mmHg

[ Melting Point ]:
30-32°C

[ Molecular Formula ]:
C₉H₆OS

[ Molecular Weight ]:
162.208

[ Flash Point ]:
137.2±20.4 °C

[ Exact Mass ]:
162.013931

[ PSA ]:
45.31000

[ LogP ]:
3.72

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.720

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by e...

Efficient synthesis of substituted vinyl ethers using the Julia olefination.

Org. Lett. 5 , 4851, (2003)

Julia olefination between alpha-alkoxy sulfones 2a-c and a wide variety of ketones or aldehydes afforded substituted vinyl ethers in 46-90% yields. Sulfones 2a-c were readily prepared in two steps fro...