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Kurarinone

Names

[ CAS No. ]:
34981-26-5

[ Name ]:
Kurarinone

[Synonym ]:
2-(2,4-Dihydroxyphenyl)-7-hydroxy-8-(2-isopropenyl-5-methyl-4-hexen-1-yl)-5-methoxy-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-
Kurarinone

Biological Activity

[Description]:

Kurarinone, a flavanoid derived from shrub Sophora flavescens, inhibits the process of experimental autoimmune encephalomyelitis via blocking Th1 and Th17 cell differentiation[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Xie L, et al. The flavonoid kurarinone inhibits clinical progression of EAE through inhibiting Th1 and Th17 cell differentiation and proliferation. Int Immunopharmacol. 2018 Sep;62:227-236.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
651.4±55.0 °C at 760 mmHg

[ Melting Point ]:
117-119℃

[ Molecular Formula ]:
C26H30O6

[ Molecular Weight ]:
438.513

[ Flash Point ]:
219.0±25.0 °C

[ Exact Mass ]:
438.204254

[ PSA ]:
96.22000

[ LogP ]:
6.30

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.597

Related Compounds