6-Azido-hexylamine

Names

[ Name ]:
6-Azido-hexylamine

[Synonym ]:
1-amino-6-azidohexane
6-azidohexylamine
6-azidohex-1-ylamine
6-azidohexaneamine
6-azidohexanamine
1-Hexanamine,6-azido

Biological Activity

[Description]:

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₄N₄

[ Molecular Weight ]:
142.20200

[ Exact Mass ]:
142.12200

[ PSA ]:
75.77000

[ LogP ]:
1.96886

Safety Information

[ HS Code ]:
2929909090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2929909090

[ Summary ]:
2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%