2,4'-PCB
Names
[ CAS No. ]:
34883-43-7
[ Name ]:
2,4'-PCB
[Synonym ]:
1-chloro-2-(4-chlorophenyl)benzene
2,4'-Dichlorobiphenyl
PCB 8
2,4'-dichlorobipenyl
1,1'-Biphenyl,2,4'-dichloro
2,4'-Dichloro-1,1'-biphenyl
2,4'-chlorobiphenyl
2,4'-PCB
Biphenyl,2,4'-dichloro
1,1'-Biphenyl, 2,4'-dichloro-
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
303.3±17.0 °C at 760 mmHg
[ Melting Point ]:
46°C
[ Molecular Formula ]:
C12H8Cl2
[ Molecular Weight ]:
223.098
[ Flash Point ]:
133.6±14.5 °C
[ Exact Mass ]:
222.000305
[ LogP ]:
5.02
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.594
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV3905000
- CHEMICAL NAME :
- Biphenyl, 2,4'-dichloro-
- CAS REGISTRY NUMBER :
- 34883-43-7
- BEILSTEIN REFERENCE NO. :
- 1946417
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C12-H8-Cl2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 24,173,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg/3D-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,94,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg/20D-I
- TOXIC EFFECTS :
- Immunological Including Allergic - decrease in humoral immune response
- REFERENCE :
- JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 9,283,1989
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg/20D-I
- TOXIC EFFECTS :
- Liver - other changes
- REFERENCE :
- JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 12,17,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 20 mg/kg/20D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Immunological Including Allergic - decrease in humoral immune response Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 9,283,1989
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 5 mg/kg/20D-I
- TOXIC EFFECTS :
- Liver - other changes
- REFERENCE :
- JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 12,17,1993
Safety Information
[ Symbol ]:
GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H373-H410
[ Precautionary Statements ]:
P260
[ Hazard Codes ]:
N: Dangerous for the environment;
[ Risk Phrases ]:
33-50/53
[ Safety Phrases ]:
35-60-61
[ RIDADR ]:
UN 3432 9/PG 2
[ RTECS ]:
DV3905000
[ HS Code ]:
2903999010
Synthetic Route
Customs
[ HS Code ]: 2903999010
[ Summary ]:
2903999010 2,3,3',4,5,6-hexachloro-1,1'-biphenyl。supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%
Articles
Biochem. Pharmacol. 30(6) , 577-88, (1981)
Microbial growth on dichlorobiphenyls chlorinated on both rings as a sole carbon and energy source.
Appl. Environ. Microbiol. 67(4) , 1953-5, (2001)
We have isolated bacterial strains capable of aerobic growth on ortho-substituted dichlorobiphenyls as sole carbon and energy sources. During growth on 2,2'-dichlorobiphenyl and 2,4'-dichlorobiphenyl ...
Temperature-dependent biotransformation of 2,4'-dichlorobiphenyl by psychrotolerant Hydrogenophaga strain IA3-A: higher temperatures prevent excess accumulation of problematic meta-cleavage products.Lett. Appl. Microbiol. 44(4) , 447-53, (2007)
The present work investigates the possibility that temperature could regulate the pattern of transformation of 2,4'-chlorobiphenyl (2,4'-CB) by psychrotolerant Hydrogenophaga sp. IA3-A.Transformation ...