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Alloferon

Names

[ CAS No. ]:
347884-61-1

[ Name ]:
Alloferon

[Synonym ]:
H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH
Alloferon
HIS-GLY-VAL-SER-GLY-HIS-GLY-GLN-HIS-GLY-VAL-HIS-GLY

Biological Activity

[Description]:

Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera)[1][2][3].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Chernysh S, et al. Antiviral and antitumor peptides from insects. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12628-32.  

[2]. Zhang X, et al. Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice. Sci Rep. 2022 Oct 6;12(1):16689.  

Chemical & Physical Properties

[ Molecular Formula ]:
C52H75N22O16

[ Molecular Weight ]:
1264.29000

[ Exact Mass ]:
1263.57000

[ PSA ]:
576.57000

Related Compounds