N,N-Dimethylglycine-d6 hydrochloride

Names

[ Name ]:
N,N-Dimethylglycine-d6 hydrochloride

[Synonym ]:
N,N-Dimethyl-d6-glycine hydrochloride
N-Methylsarcosine-dimethyl-d6 hydrochloride

Biological Activity

[Description]:

N,N-Dimethylglycine-d6 hydrochloride is the deuterium labeled N,N-Dimethylglycine[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Boiling Point ]:
190-192ºC(lit.)

[ Molecular Formula ]:
C₄H₄D₆ClNO₂

[ Molecular Weight ]:
145.62

[ Exact Mass ]:
145.07800

[ PSA ]:
40.54000

[ LogP ]:
0.43460

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport