chlorothricin

Names

[ Name ]:
chlorothricin

[Synonym ]:
Diuresal
(1S,3R,6R,7E,13R,16S,17S,21R,22R)-17-({4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-arabino-hexopyranosyl}oxy)-28-hydroxy-3,22-dimethyl-23,26-dioxo-24,27-dioxapentacyclo[23.2.1.0.0.0]octacosa-4,7,14,25(28)-tetraene-4-carboxylic acid
Chlorothiazid
Chlotride
16a,19-metheno-18H-benzo[e]naphtho[2,1-m][1,4]dioxacyclopentadecin-14-carboxylic acid, 4-[[4-O-[3-O-(3-chloro-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,2,3,4,4a,6a,7,8,9,10,12a,15,16,21,21a,21b-hexadecahydro-22-hydroxy-15,21a-dimethyl-18,21-dioxo-, (4S,4aS,6aR,11E,12aR,15R,16aS,21aR,21bR)-
chlorothiazide
Chlorthiazide
(1S,3R,6R,7E,13R,16S,17S,21R,22R)-17-({4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-arabino-hexopyranosyl}oxy)-28-hydroxy-3,22-dimethyl-23 ,26-dioxo-24,27-dioxapentacyclo[23.2.1.0.0.0]octacosa-4,7,14,25(28)-tetraene-4-carboxylic acid
Diuril
chlorothricin
Chlorosal
Chlortiazid
Clotride
6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide,1,1-dioxide
Chlorurit
16a,19-Metheno-18H-benzo[e]naphtho[2,1-m][1,4]dioxacyclopentadecin-14-carboxylic acid, 4-[[4-O-[3-O-(3-chloro-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-ar abino-hexopyranosyl]oxy]-1,2,3,4,4a,6a,7,8,9,10,12a,15,16,21,21a,21b-hexadecahydro-22-hydroxy-15,21a-dimethyl-18,21-dioxo-, (4S,4aS,6aR,11E,12aR,15R,16aS,21aR,21bR)-

Biological Activity

[Description]:

Chlorothricin, an antibiotic, is an Inhibitor of porcine-heart malate dehydrogenases[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

[References]

[1]. P W Schindler, et al. Chlorothricin, and inhibitor of porcine-heart malate dehydrogenases, discriminating between the mitochondrial and cytoplasmic isoenzyme. Eur J Biochem. 1975 Feb 21;51(2):579-85.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1050.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅₀H₆₃ClO₁₆

[ Molecular Weight ]:
955.479

[ Flash Point ]:
589.3±34.3 °C

[ Exact Mass ]:
954.380493

[ PSA ]:
223.04000

[ LogP ]:
9.13

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.619

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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