SB 611812

Names

[ Name ]:
SB 611812

Biological Activity

[Description]:

SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the treatment of cardiovascular disease[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Urotensin Receptor

[References]

[1]. Rakowski E, et al. A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blocker. J Mol Cell Cardiol. 2005 Nov;39(5):785-91.

[2]. Cosenzi A. Non peptidic urotensin II antagonists: perspectives for a new class of drugs. Cardiovasc Hematol Agents Med Chem. 2008 Apr;6(2):80-91.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₆Cl₃F₃N₂O₃S

[ Molecular Weight ]:
491.74000

[ Exact Mass ]:
489.99000

[ PSA ]:
67.02000

[ LogP ]:
6.56060

[ Storage condition ]:
-20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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