3',4',7,8-Tetrahydroxyflavone

Names

[ Name ]:
3',4',7,8-Tetrahydroxyflavone

[Synonym ]:
2-(3,4-Dihydroxy-phenyl)-7,8-dihydroxy-chromen-4-on
7,8,3',4'-tetrahydroxyflavone
2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chromen-4-one
2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4-one
transilitin
3',4',7,8-tetrahydroxyflavone
2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4h-chromen-4-on

Biological Activity

[Description]:

7,8,3′,4′-Tetrahydroxyflavone (compound 2) is a potent xanthine oxidase (XOD) inhibitor with an IC50 value of 10.488 µM[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase

[Target]

IC50: 10.488 µM (XOD)[1]

[References]

[1]. Tung YT, et al. Inhibition of xanthine oxidase by Acacia confusa extracts and their phytochemicals. J Agric Food Chem. 2010 Jan 27;58(2):781-6.

Chemical & Physical Properties

[ Density]:
1.654g/cm3

[ Boiling Point ]:
618.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀O₆

[ Molecular Weight ]:
286.24

[ Flash Point ]:
240.6ºC

[ Exact Mass ]:
286.04800

[ PSA ]:
111.13000

[ LogP ]:
2.28240

[ Index of Refraction ]:
1.767

Safety Information

[ Risk Phrases ]:
R36/37/38

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%