Cytidine 5'-diphosphate trisodium salt

Names

[ Name ]:
Cytidine 5'-diphosphate trisodium salt

[Synonym ]:
5'-CDP·Na3
Trisodium 5'-O-[(phosphonatooxy)phosphinato]cytidine
Cytidine-5'-diphosphate trisodium salt
trisodium [[5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] phosphate
5'-CDP 3Na Hydrate
Cytidine 5'-Diphosphate TrisodiuM Salt Hydrate
EINECS 251-990-8
MFCD00069770
trisodium [[5-(4-amino-2-oxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]methoxy-oxidophosphoryl] phosphate
Cytidine 5'-Diphosphate Trisodium Salt
Cytidine, 5'-(trihydrogen diphosphate), sodium salt (1:3)
tripotassium [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonatooxyphosphonate

Biological Activity

[Description]:

Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vivo]

CDP-ribitol can be used for the Diagnostics and research of CDP-l-ribitol pyrophosphorylase A (CRPPA) muscular dystrophy[3].

[References]

[1]. Moffatt BA, et, al. Purine and pyrimidine nucleotide synthesis and metabolism. Arabidopsis Book. 2002;1:e0018.

[2]. Salvador-Silva M, et, al. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J Comp Neurol. 2000 Feb 21;417(4):431-47.

[3]. Tol W, et, al. Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy. Clin Chem. 2019 Oct;65(10):1295-1306.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₂N₃Na₃O₁₁P₂

[ Molecular Weight ]:
469.122

[ Exact Mass ]:
468.964020

[ PSA ]:
252.00000

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3.0