Isoapetalic acid

Names

[ Name ]:
Isoapetalic acid

[Synonym ]:
3-[(7R,8R)-5-Hydroxy-2,2,7,8-tetramethyl-6-oxo-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-10-yl]hexanoic acid
2H,6H-Benzo[1,2-b:5,4-b']dipyran-10-propanoic acid, 7,8-dihydro-5-hydroxy-2,2,7,8-tetramethyl-6-oxo-β-propyl-, (7R,8R)-
3-[(7S,8S)-5-Hydroxy-2,2,7,8-tetramethyl-6-oxo-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-10-yl]hexanoic acid
2H,6H-Benzo[1,2-b:5,4-b']dipyran-10-propanoic acid, 7,8-dihydro-5-hydroxy-2,2,7,8-tetramethyl-6-oxo-β-propyl-, (7S,8S)-

Biological Activity

[Description]:

Isoapetalic acid (compound 4) is a potent anti-HIV agent[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[In Vitro]

Isoapetalic acid (compound 4) 具有抗 HIV 活性，对 HIV-1 RT 的抑制率为 20.6[1]。

[References]

[1]. Huerta-Reyes M, et al. HIV-1 inhibitory compounds from Calophyllum brasiliense leaves. Biol Pharm Bull. 2004 Sep;27(9):1471-5.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
586.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₈O₆

[ Molecular Weight ]:
388.45

[ Flash Point ]:
202.7±23.6 °C

[ Exact Mass ]:
388.188599

[ PSA ]:
93.06000

[ LogP ]:
6.77

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.550

Related Compounds

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