o,p'-dde
Names
[ CAS No. ]:
3424-82-6
[ Name ]:
o,p'-dde
[Synonym ]:
2,4'-DDE
O,P'-DDE
1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]benzene
Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]-
EINECS 222-318-0
2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethene
EINECS 200-659-6
1-Chloro-2-[2,2-dichloro-1-(4-chlorophényl)éthènyl]benzène
MFCD00036122
1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)vinyl]benzene
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
380.6±37.0 °C at 760 mmHg
[ Melting Point ]:
78.32°C
[ Molecular Formula ]:
C14H8Cl4
[ Molecular Weight ]:
318.025
[ Flash Point ]:
181.8±23.9 °C
[ Exact Mass ]:
315.938019
[ LogP ]:
6.22
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.622
[ Storage condition ]:
APPROX 4°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KV9454000
- CHEMICAL NAME :
- Ethylene, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-
- CAS REGISTRY NUMBER :
- 3424-82-6
- BEILSTEIN REFERENCE NO. :
- 1977640
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H8-Cl4
- MOLECULAR WEIGHT :
- 318.02
- WISWESSER LINE NOTATION :
- GYGUYR DG&R BG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 880 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - rat Cells - not otherwise specified
- DOSE/DURATION :
- 10 ug/L
- REFERENCE :
- 34LXAP "Insecticide Biochemistry and Physiology," Wilkinson, C.F., ed., New York, Plenum Pub. Corp., 1976 Volume(issue)/page/year: -,555,1976
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H311 + H331-H370
[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
F;T
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S7;S16;S24;S45
[ RIDADR ]:
UN 3077
[ RTECS ]:
KV9450000
[ Hazard Class ]:
9.0
[ HS Code ]:
2903999090
Synthetic Route
Customs
[ HS Code ]: 2903999090
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Ecotoxicol. Environ. Saf. 77 , 35-44, (2012)
Organochlorine pesticides (HCB, HCH with α-, β-, and γ isomers, heptachlor, cis-heptachlor epoxyde, trans-heptachlor epoxyde, endosulfan with α- and β isomers, sulfate endosulfan, o,p'-DDT, p,p'-DDT, ...
DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta.J. Physiol. Pharmacol. 58(4) , 873-85, (2007)
We evaluated impact of DDT isomers, o, p'- DDT [1, 1-dichloro-2, 2-bis (p, p'-chlorophenyl) ethylene] and p, p'-DDT [1, 1, 1-trichloro-2, 2-bis (p-chlorophenyl) ethane], and their metabolites, o, p'-D...
Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENS@T multicenter study.J. Clin. Endocrinol. Metab. 96(6) , 1844-51, (2011)
In patients with adrenocortical carcinoma (ACC) mitotane activity has been suggested to depend on plasma levels 14 mg/liter or greater and metabolite formation.The study was performed to confirm the c...