TERT-BUTYL 2-ISOCYANOPROPIONATE

Names

[ Name ]:
TERT-BUTYL 2-ISOCYANOPROPIONATE

[Synonym ]:
tert-Butyl 2-isocyanopropionate
Propanoic acid,2-isocyano-,1,1-dimethylethyl ester (9CI)
DL-Alanine tert-butyl ester isocyanide
2-Isocyansaeure-tert-butylester

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₃NO₂

[ Molecular Weight ]:
155.19400

[ Exact Mass ]:
155.09500

[ PSA ]:
26.30000

[ LogP ]:
0.86660

[ Index of Refraction ]:
n20/D 1.413

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H315-H317-H319-H332-H334-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22-36/37/38-42

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

A novel three-component butenolide synthesis.

Org. Lett. 3 , 2875, (2001)

[reaction: see text]. 5-Acylamino butenolides can be assembled by a multicomponent reaction (MCR) of isocyanides, glyoxals, and acetophosphonic acid diethylesters, followed by a intramolecular Wittig-...