(4-chlorophenylthio)acetic acid
Names
[ CAS No. ]:
3405-88-7
[ Name ]:
(4-chlorophenylthio)acetic acid
[Synonym ]:
2-((4-Chlorophenyl)thio)acetic acid
(4-CHLORO-PHENYLSULFANYL)-ACETIC ACID
(4-Chlorophenylthio)acetic acid
p-Chlorophenylmercaptoacetic acid
MFCD00021762
Chemical & Physical Properties
[ Density]:
1.41g/cm3
[ Boiling Point ]:
348.4ºC at 760mmHg
[ Melting Point ]:
104-107 °C(lit.)
[ Molecular Formula ]:
C8H7ClO2S
[ Molecular Weight ]:
202.65800
[ Flash Point ]:
164.5ºC
[ Exact Mass ]:
201.98600
[ PSA ]:
62.60000
[ LogP ]:
2.51670
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG1075000
- CHEMICAL NAME :
- Acetic acid, ((p-chlorophenyl)thio)-
- CAS REGISTRY NUMBER :
- 3405-88-7
- BEILSTEIN REFERENCE NO. :
- 1871569
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C8-H7-Cl-O2-S
- MOLECULAR WEIGHT :
- 202.66
- WISWESSER LINE NOTATION :
- QV1SR DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >400 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1500 mg/kg/5D-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Related to Chronic Data - death
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946
Safety Information
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ WGK Germany ]:
3
[ RTECS ]:
AG1075000