Benzo[a]pyren-6-ol
Names
[ CAS No. ]:
33953-73-0
[ Name ]:
Benzo[a]pyren-6-ol
[Synonym ]:
benzo<a>pyren-6-ol
benzo[def]chrysen-6-ol
6-Hydroxy-benzo[def]chrysen
6-hydroxybenzo<a>pyrene
Benzo[a]pyrenol-(6)
5-Hydroxy-3,4-benzopyrene
Benzo(a)pyrene,6-hydroxy
6-Hydroxy-benzo[a]pyren
Chemical & Physical Properties
[ Density]:
1.379g/cm3
[ Boiling Point ]:
527.2ºC at 760 mmHg
[ Molecular Formula ]:
C20H12O
[ Molecular Weight ]:
268.30900
[ Flash Point ]:
252.9ºC
[ Exact Mass ]:
268.08900
[ PSA ]:
20.23000
[ LogP ]:
5.44280
[ Index of Refraction ]:
1.924
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DJ8260000
- CHEMICAL NAME :
- Benzo(a)pyren-6-ol
- CAS REGISTRY NUMBER :
- 33953-73-0
- BEILSTEIN REFERENCE NO. :
- 1982121
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C20-H12-O
- MOLECULAR WEIGHT :
- 268.32
- WISWESSER LINE NOTATION :
- L D6 B6666 2AB TJ JQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4280 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Blood - leukemia Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intradermal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2400 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4290 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,3350,1976 *** REVIEWS *** TOXICOLOGY REVIEW ABSYB2 Alfred Benzon Symposium. (Nankodo Co. Ltd., POB 5272, Tokyo International 100-31, Japan) V.1- 1968- Volume(issue)/page/year: 10,261,1977
Safety Information
[ HS Code ]:
2906299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2906299090
[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%