Lorvotuzumab

Names

[ Name ]:
Lorvotuzumab

Biological Activity

[Description]:

Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds CD56 (NCAM1). Lorvotuzumab can be used to synthesize an ADC compound, Lorvotuzumab mertansine[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Lorvotuzumab mertansine (IMGN901) 是一种 ADC，可通过二硫键连接强效抗有丝分裂 (DM1) 与 CD56 靶向抗体 (Lorvotuzumab)。 Lorvotuzumab mertansine 抗肾母细胞瘤、横纹肌肉瘤和神经母细胞瘤。

[References]

[1]. James I Geller, et al. ADVL1522: A phase 2 study of lorvotuzumab mertansine (IMGN901) in children with relapsed or refractory wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, malignant peripheral nerve sheath tumor, or synovial sarcoma-A Children's Oncology Group study. Cancer. 2020 Dec 15;126(24):5303-5310.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.