2-(3,4 epoxycyclohexyl)ethyltrimethoxysilane
Names
[ CAS No. ]:
3388-04-3
[ Name ]:
2-(3,4 epoxycyclohexyl)ethyltrimethoxysilane
[Synonym ]:
4-[2-(Trimethoxysilyl)ethyl]-7-oxabicyclo[4.1.0]heptane
CE6250
Trimethoxy[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]silane
(2-(7-Oxabicyclo[4.1.0]heptan-3-yl)ethyl)trimethoxysilane
EINECS 222-217-1
trimethoxy[2-(7-oxabicyclo[4.1.0]-hept-3-yl)ethyl]silane
s530
Trimethoxy[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]silane
2-(2,2,3,4,4,4-HEXAFLUOROBUTOXY)ETHANOL
MFCD00014485
Silane, trimethoxy[2- (7-oxabicyclo[4.1.0]hept-3-yl)ethyl]-
2-(3,4-Epoxycyclohexyl)Ethyltrimethoxysilane
NUCA 186
Silane, [β-(3,4-epoxycyclohexyl)ethyl]trimethoxy-
y4086
KBM 303
A 186
e6250
2-(3,4 epoxycyclohexyl)ethyltrimethoxysilane
3-[2-(Trimethoxysilyl)ethyl]-7-oxabicyclo[4.1.0]heptane
Silane, trimethoxy[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]-
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
263.5±13.0 °C at 760 mmHg
[ Melting Point ]:
<0ºC
[ Molecular Formula ]:
C11H22O4Si
[ Molecular Weight ]:
246.376
[ Flash Point ]:
89.7±20.2 °C
[ Exact Mass ]:
246.128738
[ PSA ]:
40.22000
[ LogP ]:
1.28
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.454
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VV4000000
- CHEMICAL NAME :
- Silane, beta-(3,4-epoxycyclohexyl)ethyltrimethoxy-
- CAS REGISTRY NUMBER :
- 3388-04-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C11-H22-O4-Si
- MOLECULAR WEIGHT :
- 246.42
- WISWESSER LINE NOTATION :
- T36 BOTJ E2-SI-O1&O1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/17/1972 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JBMRBG Journal of Biomedical Materials Research. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1967- Volume(issue)/page/year: 8,11,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JBMRBG Journal of Biomedical Materials Research. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1967- Volume(issue)/page/year: 8,11,1974
- TYPE OF TEST :
- LC - Lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >290 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JBMRBG Journal of Biomedical Materials Research. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1967- Volume(issue)/page/year: 8,11,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6300 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 2/11/1964 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1587 gm/kg/76W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 12,579,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9076 No. of Facilities: 367 (estimated) No. of Industries: 17 No. of Occupations: 23 No. of Employees: 15389 (estimated) No. of Female Employees: 3865 (estimated)
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H350
[ Precautionary Statements ]:
P201-P308 + P313
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R45;R46
[ Safety Phrases ]:
S53-S23-S36/37/39-S45
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
VV4000000
[ HS Code ]:
2932999099
Customs
[ HS Code ]: 2932999099
[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Se Pu 19(6) , 485-8, (2001)
A new silane coupling agent, beta-(3,4-epoxycyclohexyl)ethyltrimethoxy silane, was for the firsty time used to react with octanol, then the intermediate product was coupled onto porous silica to obtai...
Evaluation of the developmental toxicity of beta-(3,4-epoxycyclohexyl)ethyltrimethoxysilane in Fischer 344 rats and New Zealand white rabbits.Fundam. Appl. Toxicol. 10(3) , 439-52, (1988)
beta-(3,4-epoxycyclohexyl)ethyltrimethoxysilane (ECEMS, CAS No. 3388-04-3) is mutagenic in vitro and weakly carcinogenic in mice after dermal application. Timed pregnant Fischer 344 rats and New Zeala...
Design and application of high-sensitivity two-photon initiators for three-dimensional microfabrication.J. Photochem. Photobiol. A: Chem. 158(2) , 163-170, (2003)