N,N-BIS(β-CHLOROETHYL)-dl-ALANINE HYDROCHLORIDE
Names
[ CAS No. ]:
3374-04-7
[ Name ]:
N,N-BIS(β-CHLOROETHYL)-dl-ALANINE HYDROCHLORIDE
[Synonym ]:
N,l-alanine hydrochloride
2-<Bis-(2-chlor-ethyl)-amino>-propionsaeure
N,N-Bis(2-chloroethyl)-DL-alanine hydrochloride
N-Bis-(2-chlor-aethyl)-DL-alanin,Hydrochloride
DL-Alanine,N-bis(2-chloroethyl)-,hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
248.3ºC at 760mmHg
[ Molecular Formula ]:
C7H14Cl3NO2
[ Molecular Weight ]:
250.55100
[ Flash Point ]:
104ºC
[ Exact Mass ]:
249.00900
[ PSA ]:
40.54000
[ LogP ]:
2.04110
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY4200000
- CHEMICAL NAME :
- Alanine, N,N-bis(2-chloroethyl)-, hydrochloride, DL-
- CAS REGISTRY NUMBER :
- 3374-04-7
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C7-H13-Cl2-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 250.57
- WISWESSER LINE NOTATION :
- QVY1&N2G2G &GH -R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intracerebral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 225 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,760,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1250 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Blood - leukopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 1250 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965