Pregn-17(20)-en-21-oic acid, 3,16-dihydroxy-11-oxo-, gamma-lactone, (3-beta,5-alpha,16-beta)-
Names
[ CAS No. ]:
337-67-7
[ Name ]:
Pregn-17(20)-en-21-oic acid, 3,16-dihydroxy-11-oxo-, gamma-lactone, (3-beta,5-alpha,16-beta)-
Chemical & Physical Properties
[ Density]:
1.25g/cm3
[ Boiling Point ]:
547.7ºC at 760 mmHg
[ Molecular Formula ]:
C21H28O4
[ Molecular Weight ]:
344.44500
[ Flash Point ]:
194.6ºC
[ Exact Mass ]:
344.19900
[ PSA ]:
63.60000
[ LogP ]:
3.03070
[ Index of Refraction ]:
1.585
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU5535000
- CHEMICAL NAME :
- 5-alpha-Pregn-17(20)-en-21-oic acid, 3-beta,16-beta-dihydroxy-11-oxo-, gamma-lactone
- CAS REGISTRY NUMBER :
- 337-67-7
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C21-H28-O4
- MOLECULAR WEIGHT :
- 344.49
- WISWESSER LINE NOTATION :
- T F5 E5 B666 CV HVO JH&TTTTJ A1 E1 P1 RQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 7,348,1964