Tomentosin

Names

[ Name ]:
Tomentosin

[Synonym ]:
Xanthalongin
Tomentosin
2H-Cyclohepta(b)furan-2-one, 3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-(3-oxobutyl)-, (3aR,7S,8aR)-
2H-Cyclohepta[b]furan-2-one, 3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-(3-oxobutyl)-, (3aR,7S,8aR)-
(3aR,7S,8aR)-7-Methyl-3-methylene-6-(3-oxobutyl)-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one

Biological Activity

[Description]:

Tomentosin is a antiphlogistic sesquiterpene lactone that can be isolated from Inula falconeri.Tomentosin induces Apoptosis and inhibits proliferation, migration and invasion of pancreatic cancer cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Güçlü E, et al. Tomentosin induces apoptosis in pancreatic cancer cells through increasing reactive oxygen species and decreasing mitochondrial membrane potential. Toxicol In Vitro. 2022 Oct;84:105458.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
416.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₀O₃

[ Molecular Weight ]:
248.318

[ Flash Point ]:
185.1±28.8 °C

[ Exact Mass ]:
248.141251

[ LogP ]:
2.12

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.511

Related Compounds

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