Venturicidin B

Names

[ Name ]:
Venturicidin B

[Synonym ]:
Velloquercetin

Biological Activity

[Description]:

Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Membrane Transporter/Ion Channel >> ATP Synthase

[References]

[1]. Yakov M Milgrom, et al. Complex effects of macrolide venturicidins on bacterial F-ATPases likely contribute to their action as antibiotic adjuvants. Sci Rep. 2021 Jul 1;11(1):13631.

Chemical & Physical Properties

[ Density]:
1.14g/cm3

[ Boiling Point ]:
823.4ºC at 760 mmHg

[ Molecular Formula ]:
C₄₀H₆₆O₁₀

[ Molecular Weight ]:
706.94600

[ Flash Point ]:
240.9ºC

[ Exact Mass ]:
706.46600

[ PSA ]:
151.98000

[ LogP ]:
5.94110

[ Index of Refraction ]:
1.538

Related Compounds

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