(E)-2-Decenoic acid

Names

[ CAS No. ]:
334-49-6

[ Name ]:
(E)-2-Decenoic acid

[Synonym ]:
2-Decenoic acid, (E)-
2E-decenoic acid
2-trans-decenoic acid
2-DECYLENIC ACID
EINECS 206-378-5
MFCD00039530
T2 DECENOIC ACID
FEMA NUMBER 3913
TRANS-2-DECYLENIC ACID
trans-2-Decenoic acid,tech.
RARECHEM AL BK 0166
Dec-2-enoic acid
Decenoic acid
(2E)-dec-2-enoic acid
(E)-dec-2-enoic acid
2-decenoic acid
2-Decenoic acid, (2E)-
trans-dec-2-enoic acid
(2E)-2-Decenoic acid
trans-2-Decenoic Acid
(E)-2-Decenoic acid

Biological Activity

[Description]:

(E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Cancer

[In Vitro]

(E)-2-Decenoic acid is isolated along with 10-hydroxy-trans-2-decenoic acid, a fatty acid unique to royal jelly. (E)-2-Decenoic acid and 10-hydroxy-trans-2-decenoic acid are both described to demonstrate estrogenic activity, where the fatty acids demonstrate inhibition of 17β-estradiol binding to estrogen receptor-β.

[References]

[1]. Naumowicz M, Petelska AD, Figaszewski ZA.Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine.Cell Biochem Biophys. 2011 Sep;61(1):145-55.

[2]. Kumar A, Singh S, Jain S, Kumar P.Synthesis, antimicrobial evaluation, QSAR and in Silico ADMET studies of decanoic acid derivatives.Acta Pol Pharm. 2011 Mar-Apr;68(2):191-204.

[3]. Petelska AD, Figaszewski ZA.Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems.J Membr Biol. 2011 May;241(2):103-8.

[4]. Hattori N et al.Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro. Biomed Res. 2007 Oct;28(5):261-6.

[5]. Suzuki KM et al. Estrogenic activities of Fatty acids and a sterol isolated from royal jelly. Evid Based Complement Alternat Med. 2008 Sep;5(3):295-302.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
278.6±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₈O₂

[ Molecular Weight ]:
170.249

[ Flash Point ]:
185.0±9.6 °C

[ Exact Mass ]:
170.130676

[ PSA ]:
37.30000

[ LogP ]:
3.99

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.462

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
34

[ Safety Phrases ]:
S45-S36/37/39-S25

[ HS Code ]:
2916190090

Customs

[ HS Code ]: 2916190090

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%