N'-(5-fluoro-2-oxoindolin-3-ylidene)-4-hydroxybenzohydrazide

Names

[ Name ]:
N'-(5-fluoro-2-oxoindolin-3-ylidene)-4-hydroxybenzohydrazide

Biological Activity

[Description]:

c-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. c-Met-IN-15 inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR

[References]

[1]. Liang Z, et, al. Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3749-54.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₀FN₃O₃

[ Molecular Weight ]:
299.26

[ Storage condition ]:
-20°C

Related Compounds

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