tioxazafen

Names

[ Name ]:
tioxazafen

[Synonym ]:
Tioxazafen
HMS1583K21
3-phenyl-5-(2-thienyl)-1,2,4-oxadiazole
3-phenyl-5-(thiophen-2-yl)-1,2,4-oxadiazole
3-phenyl-5-thiophen-2-yl-1,2,4-oxadiazole

Biological Activity

[Description]:

Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

Nematodes[1]

[In Vitro]

Tioxazafen has direct nematicidal activity against RKN (M. incognita) and SCN (H. glycines) and is as effective as nematicidal active ingredients of commercial standards in causing nematode mortality. Tioxazafen exhibits excellent activity against soybean cyst, root knot, and reniform nematodes in soy; lesion, root knot, and needle nematodes in corn; as well as reniform and root knot nematodes in cotton[1].

[References]

[1]. Urszula Slomczynska, et al. Tioxazafen: A New Broad-Spectrum Seed Treatment Nematicide. Discovery and Synthesis of Crop Protection Products. 2015, Chapter 10: pp 129-147.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₈N₂OS

[ Molecular Weight ]:
228.27000

[ Exact Mass ]:
228.03600

[ PSA ]:
67.16000

[ LogP ]:
3.46510

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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