Bucloxic acid

Names

[ Name ]:
Bucloxic acid

[Synonym ]:
Acide bucloxique [INN-French]
Bucloxinsaeure [German]
l'Acide bucloxique [French]
4-(3-Chloro-4-cyclohexylphenyl)-4-oxo-buttersaeure
Bucloxonic acid
Acidum bucloxicum [INN-Latin]
Esfar
EINECS 251-231-0
4-(3-chloro-4-cyclohexylphenyl)-4-oxobutyric acid
Acido bucloxico [INN-Spanish]
Bucloxic Acid
3-(3-chloro-4-cyclohexylbenzoyl)propionic acid
Bucloxinsaeure

Biological Activity

[Description]:

Bucloxic acid is an anti-inflammatory pyrrazole derivative. Bucloxic acid can be used in the treatment of chronic glomerular nephropathies.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Lagrue G, et al. Use of a new anti-inflammatory agent, bucloxic acid, in the treatment of chronic glomerular nephropathies. Arzneimittelforschung. 1974 Sep;24(9A SUPPL):1434-9.

[2]. Magous R, et al. Mol Pharmacol. 1986 Jan;29(1):39-44. Evidence for the existence of high affinity binding sites for indomethacin on human blood platelets.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.219g/cm3

[ Boiling Point ]:
482ºC at 760mmHg

[ Molecular Formula ]:
C₁₆H₁₉ClO₃

[ Molecular Weight ]:
294.77300

[ Flash Point ]:
245.3ºC

[ Exact Mass ]:
294.10200

[ PSA ]:
54.37000

[ LogP ]:
4.43520

[ Index of Refraction ]:
1.557

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2918300090

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds

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