BIO-7662
Names
[ CAS No. ]:
327613-10-5
[ Name ]:
BIO-7662
Biological Activity
[Description]:
A potent, highly selective α4β1 integrin antagonist with Kd of <10 pM; the rate of BIO7662 binding is dependent on the metal ion concentration; directly competes with VCAM-1, CS-1, and BIO1211 for binding to the integrin.
[References]
References 1. Chen LL, et al. J Biol Chem. 2001 Sep 28;276(39):36520-9. 2. Egger LA, et al. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13. View Related Products by Target Integrin
Chemical & Physical Properties
[ Molecular Formula ]:
C38H48N6O8S
[ Molecular Weight ]:
748.896
Related Compounds
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