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Isorhapontin

Names

[ CAS No. ]:
32727-29-0

[ Name ]:
Isorhapontin

[Synonym ]:
isorhapontin
isorhapontigenin-11-O-β-D-glucopyranoside
isorhapontigenin-3-O-β-D-glucopyranoside
isorhapontigenin 3-O-β-D-glucoside
trans-3,4',5-Trihydroxy-3'-methoxystilben-3-O-β-D-glucopyranosid
isorhapontigenin 3-(β-D-glucopyranoside)

Biological Activity

[Description]:

Isorhapontin is an antifungal agent. Isorhapontin inhibits the hydrolytic activity of Trichoderma cellobiohydrolase I (CBH I) with a Ki of 57.2 μM. Isorhapontin also inhibits the activity of Trichoderma endoglucanase I[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[Target]

Ki: 57.2 μM (Cellobiohydrolase I)[1]


[References]

[1]. Underwood C D T, et al. Astringin and isorhapontin distribution in Sitka spruce trees. Phytochemistry, 1991, 30(7): 2183-2189.

[2]. Shibutani S, et al. Inhibition of Trichoderma cellulase activity by a stilbene glucoside from Picea glehnii bark. Journal of wood science, 2001, 47(2): 135-140.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H24O9

[ Molecular Weight ]:
420.41000

[ Exact Mass ]:
420.14200

[ PSA ]:
149.07000

[ LogP ]:
0.45550

[ Storage condition ]:
2-8℃

Precursor & DownStream

Precursor

DownStream