B-Raf IN 14

Names

[ CAS No. ]:
326918-98-3

[ Name ]:
B-Raf IN 14

[Synonym ]:
Acetamide, 2-[[7-[(3-bromophenyl)methyl]-2,3,6,7-tetrahydro-3-methyl-2,6-dioxo-1H-purin-8-yl]thio]-

Biological Activity

[Description]:

B-Raf IN 14 (Comp 25) is a BRAF inhibitor with IC50 value of 11.08 μM, which can be used in cancer-related research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> Raf

[References]

[1]. Cheng Luo, et al. Identification of BRAF inhibitors through in silico screening. J Med Chem. 2008 Oct 9;51(19):6121-6127.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₄BrN₅O₃S

[ Molecular Weight ]:
424.27

Related Compounds

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