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WDR5-IN-6

Names

[ CAS No. ]:
326901-92-2

[ Name ]:
WDR5-IN-6

Biological Activity

[Description]:

WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

WDR5[1]


[References]

[1]. Han QL, et al. Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol Sin. 2023 Apr;44(4):877-887.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H8Cl2N2O2S

[ Molecular Weight ]:
327.19


Related Compounds

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