Fraxamoside

Names

[ Name ]:
Fraxamoside

[Synonym ]:
Methyl (1S,3S,7S,12R,15R,16S,17S,18R,20E)-12-(3,4-dihydroxyphenyl)-20-ethylidene-16,17,18-trihydroxy-9-oxo-2,4,10,13,19-pentaoxatricyclo[13.3.1.1]icos-5-ene-6-carboxylate

Biological Activity

[Description]:

Fraxamoside is a competitive xanthine oxidase inhibitor with an IC50 of 16.1 μM and a Ki of 0.9 μM[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase

[References]

[1]. Vitale RM, et al. Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor. J Enzyme Inhib Med Chem. 2017 Dec;32(1):345-354.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
825.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₀O₁₃

[ Molecular Weight ]:
538.50

[ Flash Point ]:
277.9±27.8 °C

[ Exact Mass ]:
538.168640

[ PSA ]:
190.67000

[ LogP ]:
1.26

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.614

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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