2-(4-Methylphenyl)ethanamine

Names

[ Name ]:
2-(4-Methylphenyl)ethanamine

[Synonym ]:
p-Methylphenethylamine
Benzeneethanamine,4-methyl
2-(4-Methylphenyl)ethylamine
MFCD00008195
4-Methyl-benzeneethanamine
para-methylphenethylamine
4-Methylphenethylamine
2-(4-Methylphenyl)ethanamine
EINECS 221-865-2
2-p-Tolyl-ethylamine
2-(p-Tolyl)ethylamine
Benzeneethanamine, 4-methyl-
2-(p-Tolyl)ethanamine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
214.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₃N

[ Molecular Weight ]:
135.206

[ Flash Point ]:
90.6±0.0 °C

[ Exact Mass ]:
135.104797

[ PSA ]:
26.02000

[ LogP ]:
1.92

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.533

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S37/39

[ WGK Germany ]:
3

[ HS Code ]:
2921499090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

J. Med. Chem. 48 , 440-9, (2005)

The purpose of this study was to develop screening and in silico modeling methods to obtain accurate information on the active center of CYP2A6, a nicotine oxidizing enzyme. The inhibitory potencies o...

Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.

J. Med. Chem. 48 , 3808-15, (2005)

The purpose of this study was to determine the cytochrome P450 1A2 (CYP1A2) inhibition potencies of structurally diverse compounds to create a comprehensive three-dimensional quantitative structure-ac...

Structure–activity correlations for β-phenethylamines at human trace amine receptor 1

Bioorg. Med. Chem. 16 , 7415-23, (2008)

CoMFA 3D-QSAR studies on the potency of 68 β-phenethylamine analogs to activate hTAAR 1 (61% steric, 39% electrostatic) indicates that bulk both at nitrogen and 4-aryl leads to lower potency.