6-Methoxykaempferol

Names

[ Name ]:
6-Methoxykaempferol

[Synonym ]:
Kaempferol 6-methyl ether
6-hydroxykaempferol 6-methyl ether
6-methoxy kaempferol
3,4',5,7-Tetrahydroxy-6-methoxyflavone
Kaempferol-6-methylaether
3,5,7-trihydroxy-2-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one
3,5,7,4'-tetrahydroxy-6-methoxy-flavone

Biological Activity

[Description]:

6-Methoxykaempferol is a flavone that can be found in brazilian propolis. 6-Methoxykaempferol shows anti-proliferative activity for cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

6-Methoxykaempferol (0-200 µM; 24 h) 显示抗增殖作用，对 DLD-1、MCF-7、A549 细胞的 IC50 分别为 101.8、>200、125.1 µM[1]。 Cell Proliferation Assay[1] Cell Line: DLD-1, MCF-7, A549 cells Concentration: 0-200 µM Incubation Time: 24 h Result: Showed anti-proliferative effect with IC50s of 101.8, >200, 125.1 µM for DLD-1, MCF-7, A549 cells, respectively.

[References]

[1]. Mitsui T, et al. Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells. Biosci Biotechnol Biochem. 2018 Mar;82(3):417-421.

Chemical & Physical Properties

[ Boiling Point ]:
626.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₂O₇

[ Molecular Weight ]:
316.26200

[ Exact Mass ]:
316.05800

[ PSA ]:
120.36000

[ LogP ]:
2.29100

Safety Information

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Related Compounds

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