o-cymen-5-ol
Names
[ CAS No. ]:
3228-02-2
[ Name ]:
o-cymen-5-ol
[Synonym ]:
p-isopropyl-3-methyl phenol
p-Thymol
EINECS 221-761-7
3-methyl-4-(1-methylethyl)-phenol
3-Methyl-4-(propan-2-yl)benzolol
4-Isopropyl-3-methylphenol
Phenol,3-methyl-4-(1-methylethyl)
Phenol, 3-methyl-4-(1-methylethyl)-
Biosol
o-Cymen-5y-ol
MFCD00010704
o-cymen-5-ol
Phenol, 3-methyl-4- (1-methylethyl)-
Frecide
3-Methyl-4-(propan-2-yl)phenol
3-Methyl-4-isopropylphenol
4-Isopropyl-m-cresol
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
233.8±9.0 °C at 760 mmHg
[ Melting Point ]:
111-114 °C(lit.)
[ Molecular Formula ]:
C10H14O
[ Molecular Weight ]:
150.218
[ Flash Point ]:
104.1±7.2 °C
[ Exact Mass ]:
150.104462
[ PSA ]:
20.23000
[ LogP ]:
3.28
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.523
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GZ7170000
- CHEMICAL NAME :
- o-Cymen-5-ol
- CAS REGISTRY NUMBER :
- 3228-02-2
- BEILSTEIN REFERENCE NO. :
- 1364028
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H14-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6280 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- OSDIAF Osaka Shiritsu Daigaku Igaku Zasshi. Journal of the Osaka City Medical Center. (Osaka, Japan) V.4-23, 1955-74. For publisher information, see OIGZDE. Volume(issue)/page/year: 5,111,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 184 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Skin and Appendages - hair
- REFERENCE :
- OSDIAF Osaka Shiritsu Daigaku Igaku Zasshi. Journal of the Osaka City Medical Center. (Osaka, Japan) V.4-23, 1955-74. For publisher information, see OIGZDE. Volume(issue)/page/year: 5,111,1956
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
1759
[ WGK Germany ]:
2
[ RTECS ]:
GZ7170000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2907199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2907199090
[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Mol. Pharmacol. 87(1) , 87-95, (2015)
In common with other members of the Cys-loop family of pentameric ligand-gated ion channels, 5-hydroxytryptamine type 3 receptors (5-HT3Rs) are activated by the binding of a neurotransmitter to an ext...