4,4-dimethoxy-2-methylbutan-2-ol

Names

[ Name ]:
4,4-dimethoxy-2-methylbutan-2-ol

[Synonym ]:
dimethyl acetal of 3-hydroxyisovaleric aldehyde
4,4-Dimethoxy-2-methyl-2-butanol
2-Butanol,4,4-dimethoxy-2-methyl
dimethylacetal of 3-methyl-3-hydroxy butyraldehyde
3-hydroxy-3-methylbutanal dimethyl acetal
MFCD01863506
3-hydroxy-isovaleraldehyde dimethyl acetal
3-hydroxy-isovaleraldehyd dimethyl acetale
3-hydroxyisovaleric aldehyde dimethyl acetal

Chemical & Physical Properties

[ Density]:
0.957g/cm3

[ Boiling Point ]:
206.4ºC at 760mmHg

[ Molecular Formula ]:
C₇H₁₆O₃

[ Molecular Weight ]:
148.20000

[ Flash Point ]:
78.6ºC

[ Exact Mass ]:
148.11000

[ PSA ]:
38.69000

[ LogP ]:
0.76630

[ Index of Refraction ]:
n20/D 1.4226(lit.)

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NA 1993 / PGIII

[ WGK Germany ]:
3

[ HS Code ]:
2911000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2911000000

[ Summary ]:
2911000000 acetals and hemiacetals, whether or not with other oxygen function, and their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Efficient microwave-assisted one-pot preparation of angular 2,2-dimethyl-2H-chromone containing compounds.

Tetrahedron Lett. 51(33) , 4382-4386, (2010)

A novel and efficient microwave-assisted one-pot reaction was developed to synthesize angular 2,2-dimethyl-2H-chromone containing compounds, which is the first and key step in the synthesis of potent ...

Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2',2'-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents.

Bioorg. Med. Chem. 18(18) , 6678-89, (2010)

In a continued study, 23 3'R,4'R-di-O-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP) derivatives (5-27) were synthesized, and screened for anti-HIV activity against both a non-drug-re...