1(2H)-Pyrazineacetamide, 6-chloro-3-[[2,2-difluoro-2-(2-pyridinyl)ethyl]amino]-N-[(3-fluoro-2-pyridinyl)Methyl]-2-oxo-

Names

[ Name ]:
1(2H)-Pyrazineacetamide, 6-chloro-3-[[2,2-difluoro-2-(2-pyridinyl)ethyl]amino]-N-[(3-fluoro-2-pyridinyl)Methyl]-2-oxo-

[Synonym ]:
2-{6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-oxopyrazin-1(2H)-yl}-N-[(3-fluoropyridin-2-yl)methyl]acetamide

Biological Activity

[Description]:

Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin

[References]

[1]. Morris Plains, et al. Process for the preparation of pyrazinone thrombin inhibitor and its intermediates

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆ClF₃N₆O₂

[ Molecular Weight ]:
452.81800

[ Exact Mass ]:
452.09800

[ PSA ]:
108.52000

[ LogP ]:
2.60830

Related Compounds

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