Ethyl malonyl hydrazide

Names

[ Name ]:
Ethyl malonyl hydrazide

[Synonym ]:
Ethyl 3-hydrazino-3-oxopropionate
Ethyl malonyl hydrazide
ethyl 3-hydrazino-3-oxopropanoate
Malonic acid ethyl ester hydrazide
hydrazinocarbonyl-acetic acid ethyl ester
ethyl 2-acetate
MFCD00134484

Chemical & Physical Properties

[ Density]:
1.176g/cm3

[ Boiling Point ]:
320.9ºC at 760 mmHg

[ Melting Point ]:
72-75ºC

[ Molecular Formula ]:
C₅H₁₀N₂O₃

[ Molecular Weight ]:
146.14400

[ Flash Point ]:
147.8ºC

[ Exact Mass ]:
146.06900

[ PSA ]:
81.42000

[ LogP ]:
0.02070

[ Index of Refraction ]:
1.462

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Sequential Construction of Complex Pyrrole-Pyrrole or Pyrrole-Pyrazole Systems from 1, 2-Diaza-1, 3-butadienes. Attanasi OA, et al.

Synlett 09 , 1367-70, (1999)

Regioselective role of the hydrazide moiety in the formation of complex pyrrole-pyrazole systems Attanasi OA, et al.

Tetrahedron 57(7) , 1387-94, (2001)

An E-factor minimized solvent-free protocol for the preparation of 4, 5-dihydro-5-(trifluoromethyl)-1H-pyrazoles. Buriol L, et al.

Monatsh. Chem 142(5) , 515-20, (2011)