3,4,5-TRIMETHOXYBENZAMIDE

Names

[ Name ]:
3,4,5-TRIMETHOXYBENZAMIDE

[Synonym ]:
3,4,5-trimethoxy-benzoic acid amide
5-trimethoxybenzamide
3,5-Trimethoxybenzamide
MFCD00017129
3,4,5-TRIMETHOXYBENZAMIDE
Benzamide, 3,4,5-trimethoxy-
EINECS 221-406-6
3,4,5-Trimethoxybenzolcarboxamid
3,4,5-Trimethoxy-benzoesaeure-amid
trimethylgallamide
Trimethylaethergallussaeure-amid
BENZAMIDE,3,4,5-TRIMETHOXY
3,4,5-trimethoxy-benzamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
275.4±40.0 °C at 760 mmHg

[ Melting Point ]:
179-184 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₃NO₄

[ Molecular Weight ]:
211.214

[ Flash Point ]:
104.2±23.7 °C

[ Exact Mass ]:
211.084457

[ PSA ]:
70.78000

[ LogP ]:
0.73

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.525

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV6125000

CHEMICAL NAME :: Benzamide, 3,4,5-trimethoxy-

CAS REGISTRY NUMBER :: 3086-62-2

BEILSTEIN REFERENCE NO. :: 2697325

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H13-N-O4

MOLECULAR WEIGHT :: 211.24

WISWESSER LINE NOTATION :: ZVR CO1 DO1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 12,49,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 11,639,1962

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
CV6125000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

[Studies on antiarrhythmics. I. Synthesis of 3,4,5,-trimethoxybenzamide derivatives (author's transl)].

Yao Xue Xue Bao 16(2) , 158-60, (1981)

Fragmentation of trimethoprim and other compounds containing alkoxy-phenyl groups in electrospray ionisation tandem mass spectrometry.

Eur. J. Mass Spectrom. (Chichester, Eng.) 11(1) , 73-82, (2005)

This work describes electrospray ionisation tandem mass spectrometry studies of trimethoprim and a series of structurally similar compounds containing alkoxy-phenyl groups; using accurate mass measure...

The methodology for labeling the distal cerebrospinal fluid-contacting neurons in rats.

J. Neurosci. Methods 168 , 98-103, (2008)

The distal cerebrospinal fluid-contacting neurons (dCSF-CNs) are one special type of neurons, whose bodies are in the parenchyma of the brain and processes extend into the ventricle, which suggested t...