1,1,1-TRICHLOROPROPENE-2,3-OXIDE
Names
[ CAS No. ]:
3083-23-6
[ Name ]:
1,1,1-TRICHLOROPROPENE-2,3-OXIDE
[Synonym ]:
1,2-Epoxy-3,3,3-trichloropropane
Trichloroepoxypropane
1,1,1-Trichloropropene-2,3-oxide
Oxirane,(trichloromethyl)
Trichloropropene oxide
Propane,1,1,1-trichloro-2,3-epoxy
3,3,3-trichloropropylene oxide
Trichloropropylene oxide
1,1,1-trichloro-2,3-epoxypropane
1,1,1-Trichlor-2,3-epoxy-propan
(Trichloromethyl)oxirane
Chemical & Physical Properties
[ Density]:
1.696g/cm3
[ Boiling Point ]:
149ºC at 760mmHg
[ Molecular Formula ]:
C3H3Cl3O
[ Molecular Weight ]:
161.41400
[ Flash Point ]:
64.3ºC
[ Exact Mass ]:
159.92500
[ PSA ]:
12.53000
[ LogP ]:
1.75540
[ Index of Refraction ]:
1.535
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TZ3800000
- CHEMICAL NAME :
- Propane, 1,2-epoxy-3,3,3-trichloro-
- CAS REGISTRY NUMBER :
- 3083-23-6
- BEILSTEIN REFERENCE NO. :
- 0103758
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C3-H3-Cl3-O
- MOLECULAR WEIGHT :
- 161.41
- WISWESSER LINE NOTATION :
- T3OTJ BXGGG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 142 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sister chromatid exchange
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 25 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7926 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)