Gnetuhainin I

Names

[ Name ]:
Gnetuhainin I

[Synonym ]:
1H-Indene-4,6-diol, 2-(3,5-dihydroxyphenyl)-2,3-dihydro-1-[(S)-hydroxy(4-hydroxy-3-methoxyphenyl)methyl]-3-(4-hydroxy-3-methoxyphenyl)-, (1S,2R,3S)-rel-(+)-

Biological Activity

[Description]:

Gnetuhainin I (Compound 5) is a lignin derived from Pouzolzia zeylanica. Gnetuhainin I shows good inhibitory effect on ATP citrate lyase (ACLY) (IC50=2.63 μM)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Li JL, et al. Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica. Nat Prod Res. 2023 Jun 2:1-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₂₈O₉

[ Appearance of Characters ]:
Powder

Related Compounds

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