4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-2,3-dihydro-, (2S)-

Names

[ Name ]:
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-2,3-dihydro-, (2S)-

[Synonym ]:
butin 7-O-β-D-glucoside
(2S)-2-(3,4-dihydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
butin 7-O-β-D-glucopyranoside

Biological Activity

[Description]:

Isocoreopsin (Flavanocorepsin) is an anticancer agent that can be isolated from Butea monosperma flowers[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Isocoreopsin (Flavanocorepsin) 具有清除 DPPH 自由基的活性，EC50 值为 10 μg/mL[1]。 Isocoreopsin (50-750 μg/mL; 48 h) 显示出对 HT-29 和 HepG2 细胞株的抗增殖活性[1]。

[References]

[1]. Subramaniyan B, et al. Isocoreopsin: An active constituent of n-butanol extract of Butea monosperma flowers against colorectal cancer (CRC). J Pharm Anal. 2016 Oct;6(5):318-325.

Chemical & Physical Properties

[ Density]:
1.597±0.06 g/cm3(Predicted)

[ Boiling Point ]:
779.0±60.0 °C(Predicted)

[ Molecular Formula ]:
C₂₁H₂₂O₁₀

[ Molecular Weight ]:
434.39

[ Exact Mass ]:
434.12100

[ PSA ]:
166.14000

Related Compounds

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